--- title: QUELO Whitepaper description: QUELO’s QM-based methods are revolutionizing computational drug design by improving the predictions of how well drug molecules bind with proteins. --- Whitepaper # QUELO Classical FEP failing on critical targets? Find out how to accelerate small molecule lead optimization with quantum mechanics.   ![Title Page (1)](https://kb.qsimulate.com/hubfs/Title%20Page%20(1).png "Title Page (1)") QSimulate, 2023 [mailto:info@qsimulate.com](mailto:info@qsimulate.com)